Rabbit Secondary Antibodies
ABclonal Technology PE Rabbit anti-Human CD8b mAb
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system The CD8 antigen acting as a coreceptor and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules The functional coreceptor is either a homodimer composed of two alpha chains or a heterodimer composed of one alpha and one beta chain Both alpha and beta chains share significant homology to immunoglobulin variable light chains This gene encodes the CD8 beta chain isoforms Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described A pseudogene also located on chromosome 2 has been identified
ABclonal Technology 647 Rabbit anti-Human IL-5
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils The encoded cytokine plays a major role in the regulation of eosinophil formation maturation recruitment and survival The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases This cytokine functions by binding to its receptor which is a heterodimer whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2 GM-CSF) This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4) interleukin 13 (IL13) and CSF2 This gene IL4 and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31
ABclonal Technology 488 Rabbit anti-Human CD142
This gene encodes coagulation factor III a cell surface glycoprotein essential for initiating blood coagulation It acts as a high-affinity receptor for factor VII forming a complex that triggers protease cascades via limited proteolysis Unlike other coagulation cofactors factor III is fully functional when expressed on cell surfaces such as on monocytes It has extracellular transmembrane and cytoplasmic domains Platelets and monocytes express this factor during procoagulatory and proinflammatory responses Factor III is implicated in HIV-related coagulopathy and is associated with COVID-19 severity and mortality Notably congenital deficiency of this protein has not been observed Multiple transcript variants exist due to alternative splicing
ABclonal Technology 488 Rabbit anti-Human ROR1
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia Alternative splicing results in multiple transcript variants encoding different isoforms
Jackson Immuno Research Labs Alexa Fluor 594-AffiniPure Rabbit Anti-Rat IgM µ Chain Specific (min X Hu Sr Prot)
Alexa Fluor 594-AffiniPure Rabbit Anti-Rat IgM µ Chain Specific (min X Hu Sr Prot)
Jackson Immuno Research Labs Alexa Fluor 594-AffiniPure F(ab')2 Fragment Rabbit Anti-Rat IgG (H+L) (min X Hu Sr Prot)
Alexa Fluor 594-AffiniPure F(ab')2 Fragment Rabbit Anti-Rat IgG (H+L) (min X Hu Sr Prot)
Jackson Immuno Research Labs Cy3-AffiniPure Rabbit Anti-Rat IgG (H+L) (min X Hu Sr Prot)
Cy3-AffiniPure Rabbit Anti-Rat IgG (H+L) (min X Hu Sr Prot)
Jackson Immuno Research Labs AMCA-AffiniPure Rabbit Anti-Rat IgG + IgM (H+L)
AMCA-AffiniPure Rabbit Anti-Rat IgG + IgM (H+L)
ABclonal Technology 488 Rabbit anti-Rat IgG1 Fc
Predicted to enable antigen binding activity and immunoglobulin receptor binding activity Predicted to act upstream of or within several processes including antibody-dependent cellular cytotoxicity phagocytosis and positive regulation of immune response Predicted to be located in external side of plasma membrane and extracellular space Predicted to be part of immunoglobulin complex circulating Orthologous to human IGHG1 (immunoglobulin heavy constant gamma 1 (G1m marker))
Jackson Immuno Research Labs Rhodamine (TRITC)-AffiniPure Rabbit Anti-Rat IgM µ Chain Specific (min X Hu Sr Prot)
Rhodamine (TRITC)-AffiniPure Rabbit Anti-Rat IgM µ Chain Specific (min X Hu Sr Prot)
ABclonal Technology 647 Rabbit anti-/Rat CD27
Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process Involved in negative regulation of apoptotic process and positive regulation of JNK cascade Acts upstream of or within negative regulation of T cell apoptotic process Located in external side of plasma membrane Is expressed in several structures including femur hemolymphoid system intestine pituitary gland and reproductive system Human ortholog(s) of this gene implicated in lymphoproliferative syndrome 2 Orthologous to human CD27 (CD27 molecule)
ABclonal Technology PE Rabbit anti-Rat IgG2b Fc
Enables antigen binding activity Acts upstream of or within phagocytosis positive regulation of immune response and positive regulation of phagocytosis Located in extracellular space Part of immunoglobulin complex circulating Orthologous to several human genes including IGHG1 (immunoglobulin heavy constant gamma 1 (G1m marker)) IGHG2 (immunoglobulin heavy constant gamma 2 (G2m marker)) and IGHG3 (immunoglobulin heavy constant gamma 3 (G3m marker))
Jackson Immuno Research Labs Peroxidase-AffiniPure Rabbit Anti-Rat IgG + IgM (H+L)
Peroxidase-AffiniPure Rabbit Anti-Rat IgG + IgM (H+L)
Immunoreagents Inc RABBIT A-RAT IGG AP
Secondary Antibody: Rabbit anti-rat IgG (H&L) - Affinity Pure, Host: Rabbit, Format: Liq, Label: None, Applications: WB, ELISA, IHC/ICC, IF, IP, FC
ABclonal Technology PE Rabbit anti-Rat IgG1 Fc mAb
Predicted to enable antigen binding activity and immunoglobulin receptor binding activity Predicted to act upstream of or within several processes including antibody-dependent cellular cytotoxicity phagocytosis and positive regulation of immune response Predicted to be located in external side of plasma membrane and extracellular space Predicted to be part of immunoglobulin complex circulating Orthologous to human IGHG1 (immunoglobulin heavy constant gamma 1 (G1m marker))